SwarmDock: a server for flexible protein-protein docking.
Bioinformatics
; 29(6): 807-9, 2013 Mar 15.
Article
en En
| MEDLINE
| ID: mdl-23343604
ABSTRACT
Protein-protein interactions are central to almost all biological functions, and the atomic details of such interactions can yield insights into the mechanisms that underlie these functions. We present a web server that wraps and extends the SwarmDock flexible protein-protein docking algorithm. After uploading PDB files of the binding partners, the server generates low energy conformations and returns a ranked list of clustered docking poses and their corresponding structures. The user can perform full global docking, or focus on particular residues that are implicated in binding. The server is validated in the CAPRI blind docking experiment, against the most current docking benchmark, and against the ClusPro docking server, the highest performing server currently available.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Programas Informáticos
/
Mapeo de Interacción de Proteínas
/
Complejos Multiproteicos
/
Simulación del Acoplamiento Molecular
Idioma:
En
Revista:
Bioinformatics
Asunto de la revista:
INFORMATICA MEDICA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Reino Unido