Next generation sequencing in cancer research and clinical application.
Biol Proced Online
; 15(1): 4, 2013 Feb 13.
Article
en En
| MEDLINE
| ID: mdl-23406336
ABSTRACT
The wide application of next-generation sequencing (NGS), mainly through whole genome, exome and transcriptome sequencing, provides a high-resolution and global view of the cancer genome. Coupled with powerful bioinformatics tools, NGS promises to revolutionize cancer research, diagnosis and therapy. In this paper, we review the recent advances in NGS-based cancer genomic research as well as clinical application, summarize the current integrative oncogenomic projects, resources and computational algorithms, and discuss the challenge and future directions in the research and clinical application of cancer genomic sequencing.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Biol Proced Online
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos