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P2X receptor chimeras highlight roles of the amino terminus to partial agonist efficacy, the carboxyl terminus to recovery from desensitization, and independent regulation of channel transitions.
Allsopp, Rebecca C; Farmer, Louise K; Fryatt, Alistair G; Evans, Richard J.
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  • Allsopp RC; From the Department of Cell Physiology and Pharmacology, University of Leicester, Leicester LE1 9HN, United Kingdom.
  • Farmer LK; From the Department of Cell Physiology and Pharmacology, University of Leicester, Leicester LE1 9HN, United Kingdom.
  • Fryatt AG; From the Department of Cell Physiology and Pharmacology, University of Leicester, Leicester LE1 9HN, United Kingdom.
  • Evans RJ; From the Department of Cell Physiology and Pharmacology, University of Leicester, Leicester LE1 9HN, United Kingdom. Electronic address: rje6@le.ac.uk.
J Biol Chem ; 288(29): 21412-21421, 2013 Jul 19.
Article en En | MEDLINE | ID: mdl-23740251
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes / Activación del Canal Iónico / Receptores Purinérgicos P2X1 / Receptores Purinérgicos P2X2 / Agonistas del Receptor Purinérgico P2X Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2013 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes / Activación del Canal Iónico / Receptores Purinérgicos P2X1 / Receptores Purinérgicos P2X2 / Agonistas del Receptor Purinérgico P2X Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2013 Tipo del documento: Article País de afiliación: Reino Unido