Facile and efficient synthesis of new class of imidazole derivatives via one-pot multicomponent reactions in water.
Comb Chem High Throughput Screen
; 16(10): 788-90, 2013 Dec.
Article
en En
| MEDLINE
| ID: mdl-23848311
ABSTRACT
A water-accelerated multicomponent synthesis of organic target molecules has been used as a key method for the preparation of novel imidazole derivatives. The three-component condensation reactions of primary amines with trichloroacetonitrile in the presence of ninhydrine in water are developed as efficient and clean green synthetic procedures for the high-yielding preparation of imidazoles.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Agua
/
Imidazoles
Idioma:
En
Revista:
Comb Chem High Throughput Screen
Asunto de la revista:
BIOLOGIA MOLECULAR
/
QUIMICA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Irán