Phoslactomycins from Streptomyces sp. MLA1839 and their biological activities.
J Nat Prod
; 76(8): 1509-13, 2013 Aug 23.
Article
en En
| MEDLINE
| ID: mdl-23914940
Phoslactomycins H (1) and I (2), two new members of the phoslactomycin class of chemistry, were isolated from Streptomyces sp. MLA1839 on the basis of their antifungal activities. Their structures were elucidated using extensive NMR spectroscopy and mass spectrometry. Phoslactomycin H (1) featured a rare and unprecedented N,N-dimethylamine substitution at C-4 and existed as a hydroxy acid rather than the more common lactone. Herein, we report the structure of these compounds and their biological activities.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos Organofosforados
/
Streptomyces
/
Lactonas
/
Antifúngicos
Idioma:
En
Revista:
J Nat Prod
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos