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Discovery and SAR of 5-aminooctahydrocyclopentapyrrole-3a-carboxamides as potent CCR2 antagonists.
Cai, Chaozhong; McComsey, Dave F; Hou, Cuifen; O'Neill, John C; Opas, Evan; McKenney, Sandra; Johnson, Dana; Sui, Zhihua.
Afiliación
  • Cai C; Janssen Research and Development, L.L.C. Welsh & McKean Roads, Spring House, Box 776, PA 19477, USA. Electronic address: ccai@its.jnj.com.
  • McComsey DF; Janssen Research and Development, L.L.C. Welsh & McKean Roads, Spring House, Box 776, PA 19477, USA.
  • Hou C; Janssen Research and Development, L.L.C. Welsh & McKean Roads, Spring House, Box 776, PA 19477, USA.
  • O'Neill JC; Janssen Research and Development, L.L.C. Welsh & McKean Roads, Spring House, Box 776, PA 19477, USA.
  • Opas E; Janssen Research and Development, L.L.C. Welsh & McKean Roads, Spring House, Box 776, PA 19477, USA.
  • McKenney S; Janssen Research and Development, L.L.C. Welsh & McKean Roads, Spring House, Box 776, PA 19477, USA.
  • Johnson D; Janssen Research and Development, L.L.C. Welsh & McKean Roads, Spring House, Box 776, PA 19477, USA.
  • Sui Z; Janssen Research and Development, L.L.C. Welsh & McKean Roads, Spring House, Box 776, PA 19477, USA.
Bioorg Med Chem Lett ; 24(4): 1239-42, 2014 Feb 15.
Article en En | MEDLINE | ID: mdl-23916257
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirroles / Ciclopentanos / Receptores CCR2 / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirroles / Ciclopentanos / Receptores CCR2 / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article