Adaptación Biológica; Envejecimiento/metabolismo; Enfermedad; Mitocondrias/enzimología; Estrés Oxidativo; Proteasa La/metabolismo; Regulación hacia Arriba; Animales; Humanos; Mitocondrias/metabolismo

2D-PAGE, two-dimensional polyacrylamide gel electrophoresis; AAA, ATPases associated with diverse cellular activities; Aco1, Aconitase 1; Adaptation; CDDO, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; CDDO-Me, methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate; COX, cytochrome c oxidase; COX4-1, cytochrome c oxidase subunit IV isoform 1; COX4-2, cytochrome c oxidase subunit IV isoform 2; Ccp1, mitochondrial cytochrome-c peroxidase; Clp, caseinolytic protease; ClpP, core catalytic protease unit; ERAD, endoplasmic reticulum-associated degradation; FRDA, Friedreich's ataxia; Fe/S, iron/SULFUR; HAART, highly active antiretroviral therapy; HIF-1, hypoxia inducible factor-1; HSP104, heat shock protein 104; HSP60, heat shock protein 60; Hormesis; HsIVU, bacterial ATP-dependent protease; Lon Protease; MELAS, mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes; MPPß, mitochondrial processing peptidase beta subunit; Mitochondria; NRF-2, nuclear factor (erythroid-derived 2)-like 2; Nfκb, nuclear factor kappa-light-chain-enhancer of activated B csells; Oxidative stress; PRSS15, LON gene; Pim1, ATP-dependent Lon protease from yeast; Protease La, ATP-dependent protease; Protein degradation and oxidation; Prx1, mitochondrial peroxiredoxin 1; SLLVY-AMC, N-succinyl-Leu-Leu-Val-Tyr-7-amino-4-methylcoumarin; SOD, cytosolic superoxide dismutase; SOD2, mitochondrial superoxide dismutase 2; SPG13, hereditary spastic paraplegia; WI-38, human lung fibroblast; Yjl200c, mitochondrial aconitase isozyme