A review of needle-free sumatriptan injection for rapid control of migraine.
Headache
; 53 Suppl 2: 21-33, 2013 Sep.
Article
en En
| MEDLINE
| ID: mdl-24024600
ABSTRACT
The treatment of migraine was transformed in 1992 with the introduction of the first triptan-based therapy, subcutaneous (SC) sumatriptan. SC sumatriptan has high efficacy and a rapid onset of action compared with other available triptans and formulations presumably because of its short Tmax, high Cmax, and avoidance of enteral absorption. Because of these characteristics, SC sumatriptan is still considered the most reliably and rapidly effective self-administered medication available for acute migraine. Even so, it is relatively little used possibly in part because of patient "needle-phobia." The needle-free sumatriptan injection system (Sumavel DosePro) was developed to address this concern. Clinical trials have shown that the needle-free system is bioequivalent to needle-based injection systems, easy to use, and capable of providing rapid and effective symptom relief for many migraine episodes. Sumavel DosePro is an effective treatment for migraine and should be part of the therapeutic armamentarium, particularly in cases where a rapid onset of action is critical or where oral administration is problematic.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
1_ASSA2030
Problema de salud:
1_doencas_nao_transmissiveis
Asunto principal:
Sistemas de Liberación de Medicamentos
/
Sumatriptán
/
Trastornos Migrañosos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Headache
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos