A mild synthesis of N-functionalised bromomaleimides, thiomaleimides and bromopyridazinediones.

Castañeda, Lourdes; Wright, Zoë V F; Marculescu, Cristina; Tran, Trang M; Chudasama, Vijay; Maruani, Antoine; Hull, Elizabeth A; Nunes, João P M; Fitzmaurice, Richard J; Smith, Mark E B; Jones, Lyn H; Caddick, Stephen; Baker, James R

Castañeda, Lourdes; Wright, Zoë V F; Marculescu, Cristina; Tran, Trang M; Chudasama, Vijay; Maruani, Antoine; Hull, Elizabeth A; Nunes, João P M; Fitzmaurice, Richard J; Smith, Mark E B; Jones, Lyn H; Caddick, Stephen; Baker, James R.

Afiliación

Castañeda L; Department of Chemistry, UCL, 20 Gordon St, London WC1H 0AJ, UK.

Tetrahedron Lett ; 54(27): 3493-3495, 2013 Jul 03.

Article en En | MEDLINE | ID: mdl-24058217

ABSTRACT

ABSTRACT

Bromomaleimides are useful building blocks in synthesis and powerful reagents for the selective chemical modification of proteins. A mild new synthesis of these reagents is described, along with the convenient transferability of the approach to dithiomaleimides and bromopyridazinediones.

Palabras clave

Bromomaleimides; Pyridazinediones; Reagent synthesis; Reagents for cysteine modification; Thiomaleimides

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Tetrahedron Lett Año: 2013 Tipo del documento: Article País de afiliación: Reino Unido

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