Palliative sedation in patients with advanced cancer followed at home: a prospective study.
J Pain Symptom Manage
; 47(5): 860-6, 2014 May.
Article
en En
| MEDLINE
| ID: mdl-24099896
ABSTRACT
CONTEXT Home care programs in Italy. OBJECTIVES:
The aim of this study was to assess a protocol for palliative sedation (PS) performed at home.METHODS:
A total of 219 patients were prospectively assessed to evaluate a PS protocol in patients with advanced cancer followed at home by two home care programs with different territorial facilities. The protocol was based on stepwise administration of midazolam.RESULTS:
A total of 176 of the patients died at home, and PS was performed in 24 of these patients (13.6%). Younger patients received the procedure more frequently than older patients (P=0.012). The principal reasons to start PS were agitated delirium (n=20) and dyspnea (n=4). Mean duration of PS was 42.2±30.4 hours, and the mean doses of midazolam were 23-58 mg/day. Both the home care team and the patients' relatives expressed optimal or good levels of satisfaction with the procedure in all but one case, respectively.CONCLUSION:
This protocol for PS was feasible and effective in minimizing distress for a subgroup of patients who died at home. The characteristics of patients who may be effectively sedated at home should be better explored in future studies.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cuidados Paliativos
/
Cuidado Terminal
/
Servicios de Atención de Salud a Domicilio
/
Hipnóticos y Sedantes
/
Neoplasias
Tipo de estudio:
Observational_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Pain Symptom Manage
Asunto de la revista:
NEUROLOGIA
/
PSICOFISIOLOGIA
/
TERAPEUTICA
Año:
2014
Tipo del documento:
Article