GPR120 on Kupffer cells mediates hepatoprotective effects of &#969;3-fatty acids.

Raptis, Dimitri Aristotle; Limani, Perparim; Jang, Jae Hwi; Ungethüm, Udo; Tschuor, Christoph; Graf, Rolf; Humar, Bostjan; Clavien, Pierre-Alain

GPR120 on Kupffer cells mediates hepatoprotective effects of ω3-fatty acids.

Raptis, Dimitri Aristotle; Limani, Perparim; Jang, Jae Hwi; Ungethüm, Udo; Tschuor, Christoph; Graf, Rolf; Humar, Bostjan; Clavien, Pierre-Alain.

Afiliación

Raptis DA; Department of Surgery, Laboratory of the Swiss HPB Center, University Hospital of Zurich, Switzerland.
Limani P; Department of Surgery, Laboratory of the Swiss HPB Center, University Hospital of Zurich, Switzerland.
Jang JH; Department of Surgery, Laboratory of the Swiss HPB Center, University Hospital of Zurich, Switzerland.
Ungethüm U; Department of Surgery, Laboratory of the Swiss HPB Center, University Hospital of Zurich, Switzerland.
Tschuor C; Department of Surgery, Laboratory of the Swiss HPB Center, University Hospital of Zurich, Switzerland.
Graf R; Department of Surgery, Laboratory of the Swiss HPB Center, University Hospital of Zurich, Switzerland.
Humar B; Department of Surgery, Laboratory of the Swiss HPB Center, University Hospital of Zurich, Switzerland.
Clavien PA; Department of Surgery, Laboratory of the Swiss HPB Center, University Hospital of Zurich, Switzerland. Electronic address: clavien@access.uzh.ch.

J Hepatol ; 60(3): 625-32, 2014 Mar.

Article en En | MEDLINE | ID: mdl-24262133

Asunto(s)

Aceites de Pescado/farmacología; Macrófagos del Hígado/fisiología; Hígado/efectos de los fármacos; Receptores Acoplados a Proteínas G/fisiología; Animales; Polaridad Celular; Macrófagos/fisiología; Ratones; Transducción de Señal; Triglicéridos

Palabras clave

ALT; AST; Alanine transaminase; Aspartate transaminase; Fatty acids; G protein-coupled receptor 120; GPR120; IRI; KC; Kupffer cells; Liver; O3far1; Omega-3; ROS; Reperfusion injury; i.p.; i.v.; intra-peritoneal; intra-venous; ischemia reperfusion injury; omega-3 fatty acids; reactive oxygen species; ω3FAs

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceites de Pescado / Receptores Acoplados a Proteínas G / Macrófagos del Hígado / Hígado Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Suiza

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