Pediatric pulmonary hypertension.
J Am Coll Cardiol
; 62(25 Suppl): D117-26, 2013 Dec 24.
Article
en En
| MEDLINE
| ID: mdl-24355636
ABSTRACT
Pulmonary hypertension (PH) is a rare disease in newborns, infants, and children that is associated with significant morbidity and mortality. In the majority of pediatric patients, PH is idiopathic or associated with congenital heart disease and rarely is associated with other conditions such as connective tissue or thromboembolic disease. Incidence data from the Netherlands has revealed an annual incidence and point prevalence of 0.7 and 4.4 for idiopathic pulmonary arterial hypertension and 2.2 and 15.6 for pulmonary arterial hypertension, respectively, associated with congenital heart disease (CHD) cases per million children. The updated Nice classification for PH has been enhanced to include a greater depth of CHD and emphasizes persistent PH of the newborn and developmental lung diseases, such as bronchopulmonary dysplasia and congenital diaphragmatic hernia. The management of pediatric PH remains challenging because treatment decisions continue to depend largely on results from evidence-based adult studies and the clinical experience of pediatric experts.
Palabras clave
APAH-CHD; AVT; CHD; HPAH; IPAH; PAPm; PH; PHVD; PPHN; PVR; SVR; acute vasodilator testing; congenital heart disease; hereditary pulmonary arterial hypertension; idiopathic pulmonary arterial hypertension; mean pulmonary artery pressure; pediatrics; persistent pulmonary hypertension of the newborn; pulmonary arterial hypertension associated with congenital heart disease; pulmonary hypertension; pulmonary hypertensive vascular disease; pulmonary vascular resistance; systemic vascular resistance
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hipertensión Pulmonar
Tipo de estudio:
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Animals
/
Child
/
Humans
/
Infant
/
Newborn
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Am Coll Cardiol
Año:
2013
Tipo del documento:
Article