New trial designs and potential therapies for pulmonary artery hypertension.

Gomberg-Maitland, Mardi; Bull, Todd M; Saggar, Rajeev; Barst, Robyn J; Elgazayerly, Amany; Fleming, Thomas R; Grimminger, Friedrich; Rainisio, Maurizio; Stewart, Duncan J; Stockbridge, Norman; Ventura, Carlo; Ghofrani, Ardeschir H; Rubin, Lewis J

Gomberg-Maitland, Mardi; Bull, Todd M; Saggar, Rajeev; Barst, Robyn J; Elgazayerly, Amany; Fleming, Thomas R; Grimminger, Friedrich; Rainisio, Maurizio; Stewart, Duncan J; Stockbridge, Norman; Ventura, Carlo; Ghofrani, Ardeschir H; Rubin, Lewis J.

Afiliación

Gomberg-Maitland M; Section of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois. Electronic address: mgomberg@bsd.uchicago.edu.
Bull TM; Section of Pulmonary and Critical Care, Department of Medicine, University of Colorado, Aurora, Colorado.
Saggar R; Heart and Lung Institute, Phoenix, Arizona.
Barst RJ; Columbia University, New York, New York.
Elgazayerly A; European Medicine Agency, London, England.
Fleming TR; Department of Biostatistics, University of Washington, Seattle, Washington.
Grimminger F; Section of Pulmonary, Department of Medicine, Department of Medical Oncology, University Hospital Giessen, Giessen, Germany.
Rainisio M; AbaNovus, San Remo, Italy.
Stewart DJ; Section of Cardiology, Department of Medicine, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Stockbridge N; Food and Drug Administration, White Oak, Maryland.
Ventura C; Section of Cardiology, Department of Medicine, University of Bologna, Bologna, Italy.
Ghofrani AH; Section of Pulmonary, Department of Medicine, Department of Medical Oncology, University Hospital Giessen, Giessen, Germany.
Rubin LJ; Section of Pulmonary and Critical Care, Department of Medicine, University of California San Diego, San Diego, California.

J Am Coll Cardiol ; 62(25 Suppl): D82-91, 2013 Dec 24.

Article en En | MEDLINE | ID: mdl-24355645

Asunto(s)

Ensayos Clínicos como Asunto/tendencias; Descubrimiento de Drogas/tendencias; Hipertensión Pulmonar/diagnóstico; Hipertensión Pulmonar/terapia; Proyectos de Investigación/tendencias; Animales; Ensayos Clínicos como Asunto/métodos; Hipertensión Pulmonar Primaria Familiar; Humanos

Palabras clave

6-min walk distance; 6MWD; ECMO; EPC; FAO; LV; MSC; NO; PAH; PDGF; PH; PRO; PVR; RAAS; RV; TTCW; VEGF; eNOS; endothelial nitric oxide synthase; endothelial progenitor cell; ethics; extracorporeal membrane oxygenation; fatty acid oxygenation; left ventricle/ventricular; mesenchymal stem cell; nitric oxide; patient-reported outcome; platelet-derived growth factor; pulmonary arterial hypertension; pulmonary hypertension; pulmonary vascular resistance; renin-angiotensin-aldosterone system; right ventricle/ventricular; therapeutics; time to clinical worsening; trial designs; vascular endothelial growth factor

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proyectos de Investigación / Ensayos Clínicos como Asunto / Descubrimiento de Drogas / Hipertensión Pulmonar Aspecto: Ethics / Patient_preference Límite: Animals / Humans Idioma: En Revista: J Am Coll Cardiol Año: 2013 Tipo del documento: Article

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