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South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin.
Thawer-Esmail, Fatemah; Jakasa, Ivone; Todd, Gail; Wen, Yaran; Brown, Sara J; Kroboth, Karin; Campbell, Linda E; O'Regan, Grainne M; McLean, W H Irwin; Irvine, Alan D; Kezic, Sanja; Sandilands, Aileen.
Afiliación
  • Thawer-Esmail F; Division of Dermatology, University of Cape Town, Cape Town, South Africa.
  • Jakasa I; Faculty of Food Technology and Biotechnology, Department of Chemistry and Biochemistry, Laboratory for Analytical Chemistry, University of Zagreb, Zagreb, Croatia.
  • Todd G; Department of Dermatology and Genetic Medicine, University of Dundee, Dundee, United Kingdom.
  • Wen Y; Department of Dermatology and Genetic Medicine, University of Dundee, Dundee, United Kingdom.
  • Brown SJ; Department of Dermatology and Genetic Medicine, University of Dundee, Dundee, United Kingdom.
  • Kroboth K; Department of Dermatology and Genetic Medicine, University of Dundee, Dundee, United Kingdom.
  • Campbell LE; Department of Dermatology and Genetic Medicine, University of Dundee, Dundee, United Kingdom.
  • O'Regan GM; Department of Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.
  • McLean WH; Department of Dermatology and Genetic Medicine, University of Dundee, Dundee, United Kingdom.
  • Irvine AD; Department of Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; Department of Clinical Medicine, Trinity College, Dublin, Ireland. Electronic address: irvinea@tcd.ie.
  • Kezic S; Coronel Institute of Occupational Health, Academic Medical Center, Amsterdam, The Netherlands.
  • Sandilands A; Department of Dermatology and Genetic Medicine, University of Dundee, Dundee, United Kingdom.
J Allergy Clin Immunol ; 133(1): 280-2.e1-2, 2014 Jan.
Article en En | MEDLINE | ID: mdl-24369804

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dermatitis Atópica / Epidermis / Proteínas de Filamentos Intermediarios Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Africa Idioma: En Revista: J Allergy Clin Immunol Año: 2014 Tipo del documento: Article País de afiliación: Sudáfrica

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dermatitis Atópica / Epidermis / Proteínas de Filamentos Intermediarios Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Africa Idioma: En Revista: J Allergy Clin Immunol Año: 2014 Tipo del documento: Article País de afiliación: Sudáfrica
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