Synthesis of 1-(4-aminobutyl)-2-iminoimidazolidin-4-one aimed at preparation of a creatinine-specific antibody.
Chem Pharm Bull (Tokyo)
; 62(4): 350-3, 2014.
Article
en En
| MEDLINE
| ID: mdl-24499923
ABSTRACT
For the purpose of obtaining a creatinine-specific antibody, a creatinine derivative with 4-aminobutyl, which was served as a linker for preparing the creatinine-bovine serum albumin (BSA) conjugate, was synthesized from 4-benzylaminobutan-1-ol in 8 steps. Production of anti-creatinine antibodies was observed in two rabbits using the creatinine-BSA conjugate, although their titer was rather low.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Creatinina
/
Anticuerpos
Límite:
Animals
Idioma:
En
Revista:
Chem Pharm Bull (Tokyo)
Año:
2014
Tipo del documento:
Article