Human adult dental pulp CD117/c-kit-positive networks of stromal cells.
Folia Morphol (Warsz)
; 73(1): 68-72, 2014 Feb.
Article
en En
| MEDLINE
| ID: mdl-24590525
ABSTRACT
Dental pulp tissue was collected from 6 healthy adult patients, prior to prosthetic treatments, in order to evaluate the in situ phenotype of dental pulp stromal cells and compare with that of dental pulp stem cells. A CD34-/CD44+/CD105-/CD117+/CD146-/nestin- phenotype of stromal cells in the dental pulp core was found. Cells with a similar phenotype, but CD44-, were found in the cell richzone. Dental pulp stromal networks (DPSNs) were found CD117+/CD44+ in the pulp core, but CD117+/CD44- in the cell rich zone. The c-kit-positive DPSNs were contacting pulp nerves and were, in this regard only, comparable to interstitial Cajal cells. Stromal signalling in dental pulp needs further evaluation, in normal tissue as well as a possible cause of persisting pain after endodontic treatments.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas Proto-Oncogénicas c-kit
/
Pulpa Dental
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Folia Morphol (Warsz)
Año:
2014
Tipo del documento:
Article
País de afiliación:
Rumanía