[Immunogenic activity of synthetic brucellosis antigens]. / Izuchenie immunogennoi aktivnosti iskusstvennykh brutselleznykh antigenov.
Zh Mikrobiol Epidemiol Immunobiol
; (7): 39-43, 1988 Jul.
Article
en Ru
| MEDLINE
| ID: mdl-2461012
ABSTRACT
Experimental data obtained in this investigation indicate that the conjugation of Brucella protective antigen with a polymer carrier essentially increase the immunogenic properties of the antigen. Synthesized vaccinal preparations can be of interest for practical use, as these preparations, while inducing the development of intense immunity, do not impede the diagnosis of brucellosis by serological reactions. The comparative study of the conjugates of Brucella antigen with different carriers shows that the conjugated preparation obtained on the basis of modified dextran possesses high protective potency, which makes it possible to regard this carrier as very promising for further use.
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Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
3_ND
Problema de salud:
3_neglected_diseases
/
3_zoonosis
Asunto principal:
Vacuna contra la Brucelosis
/
Vacunas
/
Vacunas Sintéticas
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
Ru
Revista:
Zh Mikrobiol Epidemiol Immunobiol
Año:
1988
Tipo del documento:
Article