[Clinical epidemiology of multiple sclerosis in Moscow. Сlinical demo-graphic characteristics in population of one region of Moscow]. / Klinicheskaia épidemiologiia rasseiannogo skleroza v Moskve. Sovremennye kliniko-demograficheskie osobennosti na primere populiatsii odnogo iz okrugov goroda.

ABSTRACT

The changes in clinical features of multiple sclerosis (MS) are noted worldwide which can be explained by diagnosis improvement and DMT implementation. Epidemiological studies of 2008-2012 in the North-West Administrative District of Moscow noted the higher proportion of women among patients of MS (MF=12.61), longer duration of the disease (mean 14.3±10.6 years, maximum - 53 years) and life expectancy of patients (44.3±12.7 years, the maximum age - 77 years). The percentage of patients with secondary progressive course of MS increased (35%). In addition, MS onset before 16 years old was diagnosed more often (5.66% of cases) and late onset MS was identified in 4.04% of the cases. Up to 45.9% of MS patients have moderate and expressed disability (group 1 and 2 disability).