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A high throughput screening assay system for the identification of small molecule inhibitors of gsp.
Bhattacharyya, Nisan; Hu, Xin; Chen, Catherine Z; Mathews Griner, Lesley A; Zheng, Wei; Inglese, James; Austin, Christopher P; Marugan, Juan J; Southall, Noel; Neumann, Susanne; Northup, John K; Ferrer, Marc; Collins, Michael T.
Afiliación
  • Bhattacharyya N; Skeletal Clinical Studies Unit, Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Hu X; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Chen CZ; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Mathews Griner LA; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Zheng W; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Inglese J; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Austin CP; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Marugan JJ; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Southall N; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Neumann S; Clinical Endocrinology Branch, Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Northup JK; Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Ferrer M; Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Collins MT; Skeletal Clinical Studies Unit, Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America.
PLoS One ; 9(3): e90766, 2014.
Article en En | MEDLINE | ID: mdl-24667240
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Subunidades alfa de la Proteína de Unión al GTP Gs / Proliferación Celular / Inhibidores Enzimáticos / Proteínas Mutantes / Bibliotecas de Moléculas Pequeñas / Ensayos Analíticos de Alto Rendimiento Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Subunidades alfa de la Proteína de Unión al GTP Gs / Proliferación Celular / Inhibidores Enzimáticos / Proteínas Mutantes / Bibliotecas de Moléculas Pequeñas / Ensayos Analíticos de Alto Rendimiento Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos