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Feedback signals in myelodysplastic syndromes: increased self-renewal of the malignant clone suppresses normal hematopoiesis.
Walenda, Thomas; Stiehl, Thomas; Braun, Hanna; Fröbel, Julia; Ho, Anthony D; Schroeder, Thomas; Goecke, Tamme W; Rath, Björn; Germing, Ulrich; Marciniak-Czochra, Anna; Wagner, Wolfgang.
Afiliación
  • Walenda T; Helmholtz Institute for Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany.
  • Stiehl T; Interdisciplinary Center of Scientific Computing (IWR), Institute of Applied Mathematics, University of Heidelberg, Heidelberg, Germany.
  • Braun H; Helmholtz Institute for Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany.
  • Fröbel J; Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • Ho AD; Department of Medicine V, Medical Center, University of Heidelberg, Heidelberg, Germany.
  • Schroeder T; Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • Goecke TW; Department of Obstetrics and Gynecology, RWTH Aachen University Medical School, Aachen, Germany.
  • Rath B; Department for Orthopedics, RWTH Aachen University Medical School, Aachen, Germany.
  • Germing U; Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • Marciniak-Czochra A; Interdisciplinary Center of Scientific Computing (IWR), Institute of Applied Mathematics, University of Heidelberg, Heidelberg, Germany.
  • Wagner W; Helmholtz Institute for Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany.
PLoS Comput Biol ; 10(4): e1003599, 2014 Apr.
Article en En | MEDLINE | ID: mdl-24763223
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndromes Mielodisplásicos / Retroalimentación / Hematopoyesis Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: PLoS Comput Biol Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2014 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndromes Mielodisplásicos / Retroalimentación / Hematopoyesis Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: PLoS Comput Biol Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2014 Tipo del documento: Article País de afiliación: Alemania