Advances in the discovery of N-acylethanolamine acid amidase inhibitors.

Bandiera, Tiziano; Ponzano, Stefano; Piomelli, Daniele

Bandiera, Tiziano; Ponzano, Stefano; Piomelli, Daniele.

Afiliación

Bandiera T; Drug Discovery and Development, Istituto Italiano di Tecnologia, Via Morego 30, I-16163 Genova, Italy. Electronic address: tiziano.bandiera@iit.it.
Ponzano S; Drug Discovery and Development, Istituto Italiano di Tecnologia, Via Morego 30, I-16163 Genova, Italy.
Piomelli D; Drug Discovery and Development, Istituto Italiano di Tecnologia, Via Morego 30, I-16163 Genova, Italy; Departments of Anatomy and Neurobiology, Pharmacology and Biological Chemistry, University of California, Irvine 92697-4625, USA. Electronic address: piomelli@uci.edu.

Pharmacol Res ; 86: 11-7, 2014 Aug.

Article en En | MEDLINE | ID: mdl-24798679

Asunto(s)

Amidohidrolasas/antagonistas & inhibidores; Analgésicos/química; Analgésicos/farmacología; Inhibidores Enzimáticos/química; Inhibidores Enzimáticos/farmacología; Amidohidrolasas/metabolismo; Analgésicos/uso terapéutico; Animales; Descubrimiento de Drogas; Inhibidores Enzimáticos/uso terapéutico; Humanos; Hiperalgesia/tratamiento farmacológico; Inflamación/tratamiento farmacológico; Dolor/tratamiento farmacológico

Palabras clave

(4-Phenylphenyl)methyl N-[(2S,3R)-2-methyl-4-oxooxetan-3-yl]carbamate (PubChem CID: 73291988); 3-Phenyl-1-pyrrolidin-1-ylpropan-1-one (PubChem CID: 1533088); 5-Phenylpentyl N-[(2S,3R)-2-methyl-4-oxooxetan-3-yl]carbamate (PubChem CID: 57523549); Fatty acid ethanolamides; Inflammation; N-Acylethanolamine acid amidase; N-Pentadecylbenzamide (PubChem CID: 44398681); N-Pentadecylcyclohexancarboxamide (PubChem CID: 44398718); N-[(3S)-2-Oxooxetan-3-yl]-3-phenylpropanamide (PubChem CID: 25227533); N-[(3S)-2-Oxooxetan-3-yl]-4-phenylbenzamide (PubChem CID: 46899632); NAAA inhibitors; Oleoylethanolamide (PubChem CID: 5283454); Pain; Palmitoylethanolamide; Palmitoylethanolamide (PubChem CID: 4671); Pentadecylamine (PubChem CID: 17386)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Amidohidrolasas / Analgésicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2014 Tipo del documento: Article

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