Current treatment modalities for spinal metastases secondary to thyroid carcinoma.
Thyroid
; 24(10): 1443-55, 2014 Oct.
Article
en En
| MEDLINE
| ID: mdl-24827757
ABSTRACT
BACKGROUND:
The spine is the most common site of bone metastases due to thyroid cancer, which develop in more than 3% of patients with well-differentiated thyroid cancer. Nearly half of patients with bone metastases from thyroid cancer develop vertebral metastases. Spinal metastases are associated with significantly reduced quality of life due to pain, neurological deficit, and increased mortality.SUMMARY:
Treatment options for patients with thyroid spinal metastases include radioiodine therapy, pharmacologic therapy, and surgical treatments, with recent advances in radiosurgery and minimally invasive spinal surgery as well. Therapeutic interventions require a multidisciplinary approach and aim to control pain, preserve or improve neurologic function, optimize local tumor control, and improve quality of life. We have proposed a three-tiered approach to the management and practical algorithms for patients with spinal metastases from thyroid carcinoma.CONCLUSIONS:
The introduction of novel and improved techniques for the treatment of spinal metastases has created the opportunity to significantly improve control of metastatic tumor growth and the quality of life for the patients with spinal metastases from thyroid cancer. In order for these options to be effectively used, a multidisciplinary approach must be applied in the management of the patients with thyroid spinal metastases.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
11_ODS3_cobertura_universal
/
6_ODS3_enfermedades_notrasmisibles
Problema de salud:
11_delivery_arrangements
/
6_endocrine_disorders
/
6_thyroid_cancer
Asunto principal:
Neoplasias de la Columna Vertebral
/
Neoplasias de la Tiroides
/
Carcinoma
Tipo de estudio:
Guideline
Aspecto:
Patient_preference
Límite:
Humans
Idioma:
En
Revista:
Thyroid
Asunto de la revista:
ENDOCRINOLOGIA
Año:
2014
Tipo del documento:
Article