Current strategic thinking for the development of a trivalent alphavirus vaccine for human use.
Am J Trop Med Hyg
; 91(3): 442-50, 2014 Sep.
Article
en En
| MEDLINE
| ID: mdl-24842880
ABSTRACT
Vaccinations against the encephalitic alphaviruses (western, eastern, and Venezuelan equine encephalitis virus) are of significant interest to biological defense, public health, and agricultural communities alike. Although vaccines licensed for veterinary applications are used in the Western Hemisphere and attenuated or inactivated viruses have been used under Investigational New Drug status to protect at-risk personnel, there are currently no licensed vaccines for use in humans. Here, we will discuss the need for a trivalent vaccine that can protect humans against all three viruses, recent progress to such a vaccine, and a strategy to continue development to Food and Drug Administration licensure.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
2_ODS3
/
3_ND
Problema de salud:
2_enfermedades_transmissibles
/
3_chikungunya
/
3_neglected_diseases
Asunto principal:
Vacunas Virales
/
Infecciones por Alphavirus
/
Alphavirus
/
Encefalitis Viral
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Am J Trop Med Hyg
Año:
2014
Tipo del documento:
Article