Benzimidazoles as Potent and Orally Active mGlu5 Receptor Antagonists with an Improved PK Profile.

Carcache, David; Vranesic, Ivo; Blanz, Joachim; Desrayaud, Sandrine; Fendt, Markus; Glatthar, Ralf

Carcache, David; Vranesic, Ivo; Blanz, Joachim; Desrayaud, Sandrine; Fendt, Markus; Glatthar, Ralf.

Afiliación

Carcache D; Global Discovery Chemistry.
Vranesic I; Neuroscience.
Blanz J; Global Discovery Chemistry.
Desrayaud S; Global Discovery Chemistry.
Fendt M; Neuroscience.
Glatthar R; Global Discovery Chemistry.

ACS Med Chem Lett ; 2(1): 58-62, 2011 Jan 13.

Article en En | MEDLINE | ID: mdl-24900255

Palabras clave

benzimidazoles; mGlu5; pharmacokinetics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACS Med Chem Lett Año: 2011 Tipo del documento: Article