Boswellia ovalifoliolata abrogates ROS mediated NF-&#954;B activation, causes apoptosis and chemosensitization in Triple Negative Breast Cancer cells.

Thummuri, Dinesh; Jeengar, Manish Kumar; Shrivastava, Shweta; Areti, Aparna; Yerra, Veera Ganesh; Yamjala, Samyuktha; Komirishetty, Prashanth; Naidu, V G M; Kumar, Ashutosh; Sistla, Ramakrishna

Boswellia ovalifoliolata abrogates ROS mediated NF-κB activation, causes apoptosis and chemosensitization in Triple Negative Breast Cancer cells.

Thummuri, Dinesh; Jeengar, Manish Kumar; Shrivastava, Shweta; Areti, Aparna; Yerra, Veera Ganesh; Yamjala, Samyuktha; Komirishetty, Prashanth; Naidu, V G M; Kumar, Ashutosh; Sistla, Ramakrishna.

Afiliación

Thummuri D; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education & Research, Balanagar, Hyderabad, Andhra Pradesh 500 037, India.
Jeengar MK; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education & Research, Balanagar, Hyderabad, Andhra Pradesh 500 037, India.
Shrivastava S; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education & Research, Balanagar, Hyderabad, Andhra Pradesh 500 037, India.
Areti A; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education & Research, Balanagar, Hyderabad, Andhra Pradesh 500 037, India.
Yerra VG; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education & Research, Balanagar, Hyderabad, Andhra Pradesh 500 037, India.
Yamjala S; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education & Research, Balanagar, Hyderabad, Andhra Pradesh 500 037, India.
Komirishetty P; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education & Research, Balanagar, Hyderabad, Andhra Pradesh 500 037, India.
Naidu VG; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education & Research, Balanagar, Hyderabad, Andhra Pradesh 500 037, India. Electronic address: vgmnaidu@niperhyd.ac.in.
Kumar A; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education & Research, Balanagar, Hyderabad, Andhra Pradesh 500 037, India.
Sistla R; Pharmacology Division, Indian Institute of Chemical Technology, Habsiguda, Hyderabad, Andhra Pradesh, India.

Environ Toxicol Pharmacol ; 38(1): 58-70, 2014 Jul.

Article en En | MEDLINE | ID: mdl-24908637

Asunto(s)

Antineoplásicos Fitogénicos/farmacología; Boswellia; Extractos Vegetales/farmacología; Apoptosis/efectos de los fármacos; Caspasa 3/metabolismo; Ciclo Celular/efectos de los fármacos; Línea Celular Tumoral; Supervivencia Celular/efectos de los fármacos; Fragmentación del ADN; Resistencia a Antineoplásicos; Femenino; Humanos; FN-kappa B/metabolismo; Hojas de la Planta; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Neoplasias de la Mama Triple Negativas; Proteína X Asociada a bcl-2/metabolismo

Palabras clave

Boswellia ovalifoliolata; Chemoresistance; NF-κB; ROS; S-phase; TNBC

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Boswellia / Antineoplásicos Fitogénicos Tipo de estudio: Etiology_studies Límite: Female / Humans Idioma: En Revista: Environ Toxicol Pharmacol Año: 2014 Tipo del documento: Article País de afiliación: India

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