Selenopeptide transamidation and metathesis.
Org Lett
; 16(15): 4032-5, 2014 Aug 01.
Article
en En
| MEDLINE
| ID: mdl-25017723
ABSTRACT
Selenopeptides can be transamidated by cysteinyl peptides in water using mild conditions (pH 5.5, 37 °C) in the presence of an arylthiol catalyst. Similar conditions also catalyze the metathesis of selenopeptides. The usefulness of the selenophosphine derived from TCEP (TCEPâSe) for inhibiting the TCEP-induced deselenization of selenocysteine residue is also reported.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Péptidos
/
Compuestos de Organoselenio
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2014
Tipo del documento:
Article
País de afiliación:
Francia