Susac-like syndrome in a chronic cocaine abuser: could levamisole play a role?
J Med Toxicol
; 11(1): 124-8, 2015 Mar.
Article
en En
| MEDLINE
| ID: mdl-25142038
ABSTRACT
INTRODUCTION:
Toxic leukoencephalopathy is a possible but rare complication of chronic cocaine abuse. The role of adulterants, mainly levamisole, is still debated. CASE REPORT We describe an atypical case of fatal leukoencephalopathy mimicking Susac syndrome in a 22-year-old man who was chronically abusing cannabis and cocaine. Exposure to levamisole as adulterant to cocaine was proven by hair analysis. Despite cessation of exposure to cocaine and aggressive immunosuppressive therapy, the patient remained in a minimally conscious state until death.DISCUSSION:
Susac syndrome is a rare entity, and its etiology is not yet fully elucidated. The toxic etiologies have been poorly investigated to date. Further observations are required to determine if cocaine and/or adulterants might play a significant role.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
2_ODS3
/
8_ODS3_consumo_sustancias_psicoactivas
Problema de salud:
2_sustancias_psicoativas
/
8_cannabis_related_disorders
/
8_cocaine_other_stimulant_related_disorders
Asunto principal:
Drogas Ilícitas
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Levamisol
/
Contaminación de Medicamentos
/
Cocaína
/
Trastornos Relacionados con Cocaína
/
Leucoencefalopatías
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
J Med Toxicol
Asunto de la revista:
TOXICOLOGIA
Año:
2015
Tipo del documento:
Article