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The protective role of NAD(P)H:quinone oxidoreductase 1 on acetaminophen-induced liver injury is associated with prevention of adenosine triphosphate depletion and improvement of mitochondrial dysfunction.
Hwang, Jung Hwan; Kim, Yong-Hoon; Noh, Jung-Ran; Gang, Gil-Tae; Kim, Kyoung-Shim; Chung, Hyo Kyun; Tadi, Surendar; Yim, Yong-Hyeon; Shong, Minho; Lee, Chul-Ho.
Afiliación
  • Hwang JH; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), University of Science and Technology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 305-806, South Korea.
  • Kim YH; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), University of Science and Technology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 305-806, South Korea.
  • Noh JR; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), University of Science and Technology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 305-806, South Korea.
  • Gang GT; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), University of Science and Technology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 305-806, South Korea.
  • Kim KS; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), University of Science and Technology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 305-806, South Korea.
  • Chung HK; Department of Internal Medicine, Research Center for Endocrine and Metabolic Diseases, Chungnam National University School of Medicine, Chungku, Daejeon, 301-721, South Korea.
  • Tadi S; Division of Metrology for Quality Life, Korea Research Institute of Standard and Science (KRISS), Daejeon, South Korea.
  • Yim YH; Division of Metrology for Quality Life, Korea Research Institute of Standard and Science (KRISS), Daejeon, South Korea.
  • Shong M; Department of Internal Medicine, Research Center for Endocrine and Metabolic Diseases, Chungnam National University School of Medicine, Chungku, Daejeon, 301-721, South Korea. minhos@cnu.ac.kr.
  • Lee CH; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), University of Science and Technology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 305-806, South Korea. chullee@kribb.re.kr.
Arch Toxicol ; 89(11): 2159-66, 2015 Nov.
Article en En | MEDLINE | ID: mdl-25224400
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_digestive_diseases Asunto principal: Adenosina Trifosfato / NAD(P)H Deshidrogenasa (Quinona) / Enfermedad Hepática Inducida por Sustancias y Drogas / Acetaminofén Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Arch Toxicol Año: 2015 Tipo del documento: Article País de afiliación: Corea del Sur
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_digestive_diseases Asunto principal: Adenosina Trifosfato / NAD(P)H Deshidrogenasa (Quinona) / Enfermedad Hepática Inducida por Sustancias y Drogas / Acetaminofén Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Arch Toxicol Año: 2015 Tipo del documento: Article País de afiliación: Corea del Sur