[A rare cause of pulmonary opacities: Lung localization of Waldenström's macroglobulinemia]. / Une cause rare d'opacités alvéolaires : maladie de Waldenström à localisation pulmonaire.
Rev Mal Respir
; 31(7): 632-5, 2014 Sep.
Article
en Fr
| MEDLINE
| ID: mdl-25239587
ABSTRACT
INTRODUCTION:
Pulmonary localized forms of Waldenström's macroglobulinemia are rare. CASE REPORT We report the observation of a 71-year-old woman with chronic cough and persisting alveolar opacities after several courses of antibiotics. Physical examination was unremarkable. Protein electrophoresis identified a monoclonal IgM in the serum. The lymphocyte immunophenotyping from the bronchoalveolar lavage was consistent with a B-cell lymphoma and Waldenström's macroglobulinemia was confirmed by the bone marrow biopsy. Chemotherapy with a combination of rituximab, fludarabine and cyclophosphamide improved the patient's symptoms and caused the pulmonary opacities to resolve. We discuss the various clinical and radiological pulmonary manifestations of this slowly progressive hematological condition.CONCLUSION:
Pulmonary manifestations of Waldenström's macroglobulinemia result in various clinical and radiological patterns. A serum protein electrophoresis should be performed in cases of pleuropulmonary opacities persisting despite antibiotics.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Macroglobulinemia de Waldenström
/
Enfermedades Pulmonares
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Aged
/
Female
/
Humans
Idioma:
Fr
Revista:
Rev Mal Respir
Año:
2014
Tipo del documento:
Article
País de afiliación:
Francia