[The lack of adherence to antiosteoporotic drugs: crossing methods, the key to adherence measurement?]. / Défaut d'observance aux médicaments antiostéoporotiques: croisement de deux techniques, la clef pour l'évaluation de l'observance ?

ABSTRACT

OBJECTIVE: To use two different techniques to assess adherence of patients treated with antiosteoporotic drug. METHODS: This monocentric transversal study was performed on a 6 months period, on patients of a single French pharmacy treated with antiosteoporotic drugs. Adherence was assessed crossing 2 techniques (patient autoquestionnaire and medication possession ratio measurement). Statistical analysis consisted in a description of the population study and a multivariate logistic regression to identify the factors associated with a lack of observance. RESULTS: Using the two techniques, the lack of adherence was estimated to be between 14 and 55%. Adherence was better in patients who were given dietetic advice or information about the usefulness of physical activity and worse in patients who reached menopause less than 23 years ago. CONCLUSION: A better identification of patients with a lack of observance is possible by crossing several techniques to assess adherence of the patient to his antiosteoporotic drug.