[Taxonomic status of the Artashat virus (ARTSV) (Bunyaviridae, Nairovirus) isolated from the ticks Ornithodoros alactagalis Issaakjan, 1936 and O. verrucosus Olenev, Sassuchin et Fenuk, 1934 (Argasidae Koch, 1844) collected in Transcaucasia].
Vopr Virusol
; 59(3): 24-8, 2014.
Article
en Ru
| MEDLINE
| ID: mdl-25335415
ABSTRACT
The Artashat virus (ARTSV) was originally isolated fom the Ornithodoros alactagalis Issaakjan, 1936 (Argasidae Koch, 1844), which were collected in the burrow of small five-toed jerboa (Allactaga elater Lichtenstein, 1825) in Armenia in 1972. Later, the ARTSV was isolated from the O. verrucosus Olenev, Sassuchin et Fenuk, 1934 collected in the burrows of Persian gerbil (Meriones persicus Blanford, 1875) in Azerbaijan. Based on the virion morphology, the ARTSV was assigned to the Bunyaviridae viruses. In this work, the ARTSV genome was partially sequenced (GenBank ID KF801650) and it was shown that the ARTSV is a new member of the Nairovirus genus. ARTSV has from 42% (Issyk-Kul virus) to 58% (Raza virus, Hughes group) similarity with the nairoviruses for nucleotide sequence of part of RNA-dependent RNA-polymerase (RdRp). The similarity on the amino acid level is 65-70%. Low level of homology and the equidistant position of the ARTSV on phylogenetic tree indicate that the ARTSV is a new prototype species of the Nairovirus genus (Bunyaviridae) forming a separate phylogenetic branch.
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Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
3_ND
Problema de salud:
3_zoonosis
Asunto principal:
Filogenia
/
Enfermedades de los Roedores
/
Gerbillinae
/
Nairovirus
/
Genoma Viral
/
Infecciones por Bunyaviridae
/
Argasidae
/
Ornithodoros
Límite:
Animals
País/Región como asunto:
Europa
Idioma:
Ru
Revista:
Vopr Virusol
Año:
2014
Tipo del documento:
Article