Omalizumab treatment in patient with severe asthma and Eosinophilic Granulomatosis with Polyangiitis . A case report.
Eur Ann Allergy Clin Immunol
; 46(6): 226-8, 2014 Nov.
Article
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| MEDLINE
| ID: mdl-25398166
ABSTRACT
Eosinophilic Granulomatosis with Polyangiitis (EGPA), formerly named Churg Strauss Syndrome, is a multisystem disorder characterized by chronic rhinosinusitis, asthma, and prominent peripheral blood eosinophilia; it is classified as a vasculitis of the small and medium sized arteries, although the vasculitis is often not clinically apparent in the initial phases of the disease. We present the case of a woman with EGPA who was frequently treated with high dose steroid therapy during hospital admission for refractory asthma. After December 2008, the date when we started Omalizumab, we observed a significative reduction of circulating eosinophils and IgE serum level, and the patient was no more hospitalized for respiratory failure or asthma attacks.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Asma
/
Síndrome de Churg-Strauss
/
Anticuerpos Antiidiotipos
/
Anticuerpos Monoclonales Humanizados
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Eur Ann Allergy Clin Immunol
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2014
Tipo del documento:
Article