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Jaridonin-induced G2/M phase arrest in human esophageal cancer cells is caused by reactive oxygen species-dependent Cdc2-tyr15 phosphorylation via ATM-Chk1/2-Cdc25C pathway.
Ma, Yong-Cheng; Su, Nan; Shi, Xiao-Jing; Zhao, Wen; Ke, Yu; Zi, Xiaolin; Zhao, Ning-Min; Qin, Yu-Hua; Zhao, Hong-Wei; Liu, Hong-Min.
Afiliación
  • Ma YC; Clinical Pharmacology Laboratory, Henan Province People's Hospital, No. 7, Wei Wu Road, Zhengzhou, Henan, China.
  • Su N; Department of Quality Detection and Management, Henan University of Animal Husbandry and Economy, Zhengzhou, Henan, China.
  • Shi XJ; School of Pharmaceutical Sciences, Zhengzhou University, No. 100, Science Avenue, Zhengzhou, Henan, China.
  • Zhao W; School of Pharmaceutical Sciences, Zhengzhou University, No. 100, Science Avenue, Zhengzhou, Henan, China.
  • Ke Y; School of Pharmaceutical Sciences, Zhengzhou University, No. 100, Science Avenue, Zhengzhou, Henan, China.
  • Zi X; Department of Urology, University of California, Irvine, Orange, CA, USA; Department of Pharmacology, University of California, Irvine, Orange, CA, USA; Department of Pharmaceutical Sciences, University of California, Irvine, Orange, CA, USA.
  • Zhao NM; Clinical Pharmacology Laboratory, Henan Province People's Hospital, No. 7, Wei Wu Road, Zhengzhou, Henan, China.
  • Qin YH; Clinical Pharmacology Laboratory, Henan Province People's Hospital, No. 7, Wei Wu Road, Zhengzhou, Henan, China.
  • Zhao HW; Clinical Pharmacology Laboratory, Henan Province People's Hospital, No. 7, Wei Wu Road, Zhengzhou, Henan, China.
  • Liu HM; School of Pharmaceutical Sciences, Zhengzhou University, No. 100, Science Avenue, Zhengzhou, Henan, China. Electronic address: liuhm@zzu.edu.cn.
Toxicol Appl Pharmacol ; 282(2): 227-36, 2015 Jan 15.
Article en En | MEDLINE | ID: mdl-25450480
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Quinasas / Neoplasias Esofágicas / División Celular / Fase G2 / Proteína Quinasa CDC2 / Especies Reactivas de Oxígeno / Diterpenos de Tipo Kaurano / Proteínas de la Ataxia Telangiectasia Mutada / Quinasa de Punto de Control 2 / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Toxicol Appl Pharmacol Año: 2015 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Quinasas / Neoplasias Esofágicas / División Celular / Fase G2 / Proteína Quinasa CDC2 / Especies Reactivas de Oxígeno / Diterpenos de Tipo Kaurano / Proteínas de la Ataxia Telangiectasia Mutada / Quinasa de Punto de Control 2 / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Toxicol Appl Pharmacol Año: 2015 Tipo del documento: Article País de afiliación: China