Concise synthesis of the C15-C38 fragment of okadaic acid: application of the Suzuki-Miyaura reaction to spiroacetal synthesis.
Org Lett
; 17(2): 366-9, 2015 Jan 16.
Article
en En
| MEDLINE
| ID: mdl-25544331
ABSTRACT
A concise synthetic entry to the C15-C38 fragment of okadaic acid by exploiting a Suzuki-Miyaura reaction for the rapid assembly of the spiroacetal substructures has been developed. The present synthesis was completed in 19 linear steps from a commercially available material, showcasing the efficiency of our synthetic strategy.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos de Espiro
/
Ácido Ocadaico
/
Acetales
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Japón
