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Direct inhibitors of InhA are active against Mycobacterium tuberculosis.
Manjunatha, Ujjini H; S Rao, Srinivasa P; Kondreddi, Ravinder Reddy; Noble, Christian G; Camacho, Luis R; Tan, Bee H; Ng, Seow H; Ng, Pearly Shuyi; Ma, Ng L; Lakshminarayana, Suresh B; Herve, Maxime; Barnes, Susan W; Yu, Weixuan; Kuhen, Kelli; Blasco, Francesca; Beer, David; Walker, John R; Tonge, Peter J; Glynne, Richard; Smith, Paul W; Diagana, Thierry T.
Afiliación
  • Manjunatha UH; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore. Yong Loo Lin School of Medicine, National University of Singapore, 119228 Singapore, Singapore. manjunatha.ujjini@novartis.com thierry.diagana@novartis.com.
  • S Rao SP; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Kondreddi RR; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Noble CG; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Camacho LR; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Tan BH; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Ng SH; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Ng PS; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Ma NL; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Lakshminarayana SB; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Herve M; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Barnes SW; Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA.
  • Yu W; Institute of Chemical Biology & Drug Discovery, Stony Brook University, Stony Brook, NY 11794-3400, USA.
  • Kuhen K; Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA.
  • Blasco F; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Beer D; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Walker JR; Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA.
  • Tonge PJ; Institute of Chemical Biology & Drug Discovery, Stony Brook University, Stony Brook, NY 11794-3400, USA.
  • Glynne R; Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA.
  • Smith PW; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore.
  • Diagana TT; Novartis Institute for Tropical Diseases, 138670 Singapore, Singapore. Yong Loo Lin School of Medicine, National University of Singapore, 119228 Singapore, Singapore. manjunatha.ujjini@novartis.com thierry.diagana@novartis.com.
Sci Transl Med ; 7(269): 269ra3, 2015 Jan 07.
Article en En | MEDLINE | ID: mdl-25568071
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_enfermedades_transmissibles Asunto principal: Oxidorreductasas / Proteínas Bacterianas / Inhibidores Enzimáticos / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_enfermedades_transmissibles Asunto principal: Oxidorreductasas / Proteínas Bacterianas / Inhibidores Enzimáticos / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article