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Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.
Ahronian, Leanne G; Sennott, Erin M; Van Allen, Eliezer M; Wagle, Nikhil; Kwak, Eunice L; Faris, Jason E; Godfrey, Jason T; Nishimura, Koki; Lynch, Kerry D; Mermel, Craig H; Lockerman, Elizabeth L; Kalsy, Anuj; Gurski, Joseph M; Bahl, Samira; Anderka, Kristin; Green, Lisa M; Lennon, Niall J; Huynh, Tiffany G; Mino-Kenudson, Mari; Getz, Gad; Dias-Santagata, Dora; Iafrate, A John; Engelman, Jeffrey A; Garraway, Levi A; Corcoran, Ryan B.
Afiliación
  • Ahronian LG; Massachusetts General Hospital Cancer Center, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Sennott EM; Massachusetts General Hospital Cancer Center, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Van Allen EM; Dana Farber Cancer Institute, Boston, Massachusetts. Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
  • Wagle N; Dana Farber Cancer Institute, Boston, Massachusetts. Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
  • Kwak EL; Massachusetts General Hospital Cancer Center, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Faris JE; Massachusetts General Hospital Cancer Center, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Godfrey JT; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
  • Nishimura K; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
  • Lynch KD; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
  • Mermel CH; Massachusetts General Hospital Cancer Center, Boston, Massachusetts. Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
  • Lockerman EL; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
  • Kalsy A; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
  • Gurski JM; Massachusetts General Hospital Cancer Center, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Bahl S; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
  • Anderka K; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
  • Green LM; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
  • Lennon NJ; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
  • Huynh TG; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
  • Mino-Kenudson M; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
  • Getz G; Massachusetts General Hospital Cancer Center, Boston, Massachusetts. Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
  • Dias-Santagata D; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
  • Iafrate AJ; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
  • Engelman JA; Massachusetts General Hospital Cancer Center, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Garraway LA; Dana Farber Cancer Institute, Boston, Massachusetts. Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
  • Corcoran RB; Massachusetts General Hospital Cancer Center, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts. rbcorcoran@partners.org.
Cancer Discov ; 5(4): 358-67, 2015 Apr.
Article en En | MEDLINE | ID: mdl-25673644
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Resistencia a Antineoplásicos / Sistema de Señalización de MAP Quinasas / Proteínas Proto-Oncogénicas B-raf / Inhibidores de Proteínas Quinasas / Mutación / Antineoplásicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Cancer Discov Año: 2015 Tipo del documento: Article
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Resistencia a Antineoplásicos / Sistema de Señalización de MAP Quinasas / Proteínas Proto-Oncogénicas B-raf / Inhibidores de Proteínas Quinasas / Mutación / Antineoplásicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Cancer Discov Año: 2015 Tipo del documento: Article