Duplex DNA and DNA-RNA hybrids with parallel strand orientation: 2'-deoxy-2'-fluoroisocytidine, 2'-deoxy-2'-fluoroisoguanosine, and canonical nucleosides with 2'-fluoro substituents cause unexpected changes on the double helix stability.

Ingale, Sachin A; Leonard, Peter; Tran, Quang Nhat; Seela, Frank

Ingale, Sachin A; Leonard, Peter; Tran, Quang Nhat; Seela, Frank.

Afiliación

Ingale SA; Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstrasse 11, 48149 Münster, Germany.
Leonard P; Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstrasse 11, 48149 Münster, Germany.
Tran QN; Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstrasse 11, 48149 Münster, Germany.
Seela F; Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstrasse 11, 48149 Münster, Germany.

J Org Chem ; 80(6): 3124-38, 2015 Mar 20.

Article en En | MEDLINE | ID: mdl-25742047

Asunto(s)

Citidina/análogos & derivados; ADN/química; Guanosina/análogos & derivados; Nucleósidos/química; ARN/química; Citidina/química; Guanosina/química; Conformación de Ácido Nucleico

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / ARN / Citidina / Guanosina / Nucleósidos Idioma: En Revista: J Org Chem Año: 2015 Tipo del documento: Article País de afiliación: Alemania

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google