Increased O-GlcNAcylation of NF-&#954;B Enhances Retinal Ganglion Cell Death in Streptozotocin-induced Diabetic Retinopathy.

Kim, Seong-Jae; Yoo, Woong-Sun; Choi, Meeyoung; Chung, Inyoung; Yoo, Ji-Myong; Choi, Wan-Sung

Increased O-GlcNAcylation of NF-κB Enhances Retinal Ganglion Cell Death in Streptozotocin-induced Diabetic Retinopathy.

Kim, Seong-Jae; Yoo, Woong-Sun; Choi, Meeyoung; Chung, Inyoung; Yoo, Ji-Myong; Choi, Wan-Sung.

Afiliación

Kim SJ; a Department of Ophthalmology , School of Medicine, Gyeongsang National University , Jinju , Korea .
Yoo WS; b Institute of Health Science, Gyeongsang National University , Jinju , South Korea and.
Choi M; a Department of Ophthalmology , School of Medicine, Gyeongsang National University , Jinju , Korea .
Chung I; b Institute of Health Science, Gyeongsang National University , Jinju , South Korea and.
Yoo JM; c Department of Anatomy and Neurobiology , School of Medicine, Gyeongsang National University , Jinju , Korea.
Choi WS; a Department of Ophthalmology , School of Medicine, Gyeongsang National University , Jinju , Korea .

Curr Eye Res ; 41(2): 249-57, 2016.

Article en En | MEDLINE | ID: mdl-25835259

Asunto(s)

Acetilglucosaminidasa/metabolismo; Apoptosis; Diabetes Mellitus Experimental/metabolismo; Retinopatía Diabética/metabolismo; N-Acetilglucosaminiltransferasas/metabolismo; Células Ganglionares de la Retina/patología; Factor de Transcripción ReIA/metabolismo; Acilación; Animales; Glucemia/metabolismo; Western Blotting; Diabetes Mellitus Experimental/patología; Retinopatía Diabética/patología; Hiperglucemia/metabolismo; Inmunoprecipitación; Etiquetado Corte-Fin in Situ; Masculino; Ratones; Ratones Endogámicos C57BL

Palabras clave

Diabetes; NF-κB; O-GlcNAcylation; ganglion cell death; retinopathy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_cardiovascular_diseases / 6_diabetes / 6_endocrine_disorders Asunto principal: Células Ganglionares de la Retina / Acetilglucosaminidasa / N-Acetilglucosaminiltransferasas / Apoptosis / Diabetes Mellitus Experimental / Retinopatía Diabética / Factor de Transcripción ReIA Límite: Animals Idioma: En Revista: Curr Eye Res Año: 2016 Tipo del documento: Article

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