Multiple endocrine neoplasia syndromes 1 and 2: manifestations and management in childhood and adolescence.
Arch Dis Child
; 100(10): 994-9, 2015 Oct.
Article
en En
| MEDLINE
| ID: mdl-25854874
ABSTRACT
The identification of the genetic causes of the multiple endocrine neoplasia (MEN) syndromes 1 and 2, and associated genotype-phenotype relationships, has revolutionised the clinical care of affected patients. A genetic diagnosis can be made during infancy and careful clinical surveillance, coupled with early intervention, has the potential to improve both morbidity and mortality. These developments have seen the management of patients with MEN move into the arena of paediatric medicine. In this review article, we consider the genetic causes of MEN together with the clinical manifestations and management of these syndromes.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
2_ODS3
/
6_ODS3_enfermedades_notrasmisibles
Problema de salud:
2_muertes_prematuras_enfermedades_notrasmisibles
/
2_muertes_prevenibles
/
6_endocrine_disorders
/
6_other_malignant_neoplasms
Asunto principal:
Neoplasia Endocrina Múltiple
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Adolescent
/
Child
/
Humans
Idioma:
En
Revista:
Arch Dis Child
Año:
2015
Tipo del documento:
Article
País de afiliación:
Reino Unido