Genetic Background is a Key Determinant of Glomerular Extracellular Matrix Composition and Organization.

Randles, Michael J; Woolf, Adrian S; Huang, Jennifer L; Byron, Adam; Humphries, Jonathan D; Price, Karen L; Kolatsi-Joannou, Maria; Collinson, Sophie; Denny, Thomas; Knight, David; Mironov, Aleksandr; Starborg, Toby; Korstanje, Ron; Humphries, Martin J; Long, David A; Lennon, Rachel

Randles, Michael J; Woolf, Adrian S; Huang, Jennifer L; Byron, Adam; Humphries, Jonathan D; Price, Karen L; Kolatsi-Joannou, Maria; Collinson, Sophie; Denny, Thomas; Knight, David; Mironov, Aleksandr; Starborg, Toby; Korstanje, Ron; Humphries, Martin J; Long, David A; Lennon, Rachel.

Afiliación

Randles MJ; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom; Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom;
Woolf AS; Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom;
Huang JL; Developmental Biology and Cancer Program, Institute of Child Health, University College London, London, United Kingdom;
Byron A; Edinburgh Cancer Research United Kingdom Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom; and.
Humphries JD; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom;
Price KL; Developmental Biology and Cancer Program, Institute of Child Health, University College London, London, United Kingdom;
Kolatsi-Joannou M; Developmental Biology and Cancer Program, Institute of Child Health, University College London, London, United Kingdom;
Collinson S; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom;
Denny T; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom; Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom;
Knight D; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom;
Mironov A; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom;
Starborg T; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom;
Korstanje R; The Jackson Laboratory, Bar Harbor, Maine.
Humphries MJ; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom;
Long DA; Developmental Biology and Cancer Program, Institute of Child Health, University College London, London, United Kingdom;
Lennon R; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom; Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom; Rachel.Lennon@manchester.ac.uk.

J Am Soc Nephrol ; 26(12): 3021-34, 2015 Dec.

Article en En | MEDLINE | ID: mdl-25896609

Asunto(s)

Matriz Extracelular/genética; Matriz Extracelular/metabolismo; Enfermedades Renales/genética; Glomérulos Renales/metabolismo; Albuminuria/genética; Albuminuria/metabolismo; Animales; Colágeno Tipo I/genética; Colágeno Tipo I/metabolismo; Quinasa 5 Dependiente de la Ciclina/metabolismo; Matriz Extracelular/ultraestructura; Femenino; Factor 2 de Crecimiento de Fibroblastos/genética; Factor 2 de Crecimiento de Fibroblastos/metabolismo; Predisposición Genética a la Enfermedad; Membrana Basal Glomerular/ultraestructura; Enfermedades Renales/metabolismo; Receptores X del Hígado; Masculino; Metaloproteinasas de la Matriz/metabolismo; Metaloendopeptidasas/genética; Metaloendopeptidasas/metabolismo; Ratones; Ratones Endogámicos; Factor 2 Relacionado con NF-E2/metabolismo; Factores de Crecimiento Nervioso/genética; Factores de Crecimiento Nervioso/metabolismo; Netrinas; Análisis de Secuencia por Matrices de Oligonucleótidos; Receptores Nucleares Huérfanos/metabolismo; ARN/análisis; Factores Sexuales; Transducción de Señal; Tenascina/genética; Tenascina/metabolismo

Palabras clave

albuminuria; cell-matrix-interactions; extracellular matrix

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Matriz Extracelular / Enfermedades Renales / Glomérulos Renales Tipo de estudio: Prognostic_studies Idioma: En Revista: J Am Soc Nephrol Asunto de la revista: NEFROLOGIA Año: 2015 Tipo del documento: Article

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