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APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells.
Cagnetta, Antonia; Caffa, Irene; Acharya, Chirag; Soncini, Debora; Acharya, Prakrati; Adamia, Sophia; Pierri, Ivana; Bergamaschi, Micaela; Garuti, Anna; Fraternali, Giulio; Mastracci, Luca; Provenzani, Alessandro; Zucal, Chiara; Damonte, Gianluca; Salis, Annalisa; Montecucco, Fabrizio; Patrone, Franco; Ballestrero, Alberto; Bruzzone, Santina; Gobbi, Marco; Nencioni, Alessio; Cea, Michele.
Afiliación
  • Cagnetta A; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy. Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
  • Caffa I; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy.
  • Acharya C; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
  • Soncini D; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy.
  • Acharya P; Mount Auburn Hospital, Harvard Medical School, Cambridge, Massachusetts.
  • Adamia S; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
  • Pierri I; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy.
  • Bergamaschi M; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy.
  • Garuti A; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy.
  • Fraternali G; Laboratories Department, Pathology Unit, IRCCS AUO S. Martino-IST, Genoa, Italy.
  • Mastracci L; Department of Surgical and Diagnostic Sciences (DISC), Pathology Unit, IRCCS AUO S. Martino-IST, Genoa, Italy.
  • Provenzani A; Center for Integrative Biology, University of Trento, Trento, Italy.
  • Zucal C; Department of Experimental Medicine, Section of Biochemistry, and CEBR, University of Genoa, Italy.
  • Damonte G; Department of Experimental Medicine, Section of Biochemistry, and CEBR, University of Genoa, Italy.
  • Salis A; Department of Experimental Medicine, Section of Biochemistry, and CEBR, University of Genoa, Italy.
  • Montecucco F; Division of Cardiology, Department of Internal Medicine, Foundation for Medical Researchers, University of Geneva, Geneva, Switzerland. Department of Medical Specialties, University of Geneva, Geneva, Switzerland.
  • Patrone F; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy.
  • Ballestrero A; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy.
  • Bruzzone S; Department of Experimental Medicine, Section of Biochemistry, and CEBR, University of Genoa, Italy.
  • Gobbi M; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy.
  • Nencioni A; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy. michele.cea@unige.it alessio.nencioni@unige.it.
  • Cea M; Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy. Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts. michele.cea@unige.it alessio.nencioni@unige.it.
Clin Cancer Res ; 21(17): 3934-45, 2015 Sep 01.
Article en En | MEDLINE | ID: mdl-25964294
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_congenital_chromosomal_anomalies / 6_leukemia Asunto principal: Piperidinas / Acrilamidas / Leucemia / Ciclosporina / Estrés del Retículo Endoplásmico / Mitocondrias / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_congenital_chromosomal_anomalies / 6_leukemia Asunto principal: Piperidinas / Acrilamidas / Leucemia / Ciclosporina / Estrés del Retículo Endoplásmico / Mitocondrias / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article