Diaminothiazoles evade multidrug resistance in cancer cells and xenograft tumour models and develop transient specific resistance: understanding the basis of broad-spectrum versus specific resistance.

Vasudevan, Smreti; Thomas, Sannu Ann; Sivakumar, Krishnankutty C; Komalam, Reena J; Sreerekha, Keerthi V; Rajasekharan, Kallikat N; Sengupta, Suparna

Vasudevan, Smreti; Thomas, Sannu Ann; Sivakumar, Krishnankutty C; Komalam, Reena J; Sreerekha, Keerthi V; Rajasekharan, Kallikat N; Sengupta, Suparna.

Afiliación

Vasudevan S; Division of Cancer Research and Distributed Information Sub-Centre, Rajiv Gandhi Centre for Biotechnology, Trivandrum, India and Department of Chemistry, University of Kerala, Trivandrum, India.
Thomas SA; Division of Cancer Research and Distributed Information Sub-Centre, Rajiv Gandhi Centre for Biotechnology, Trivandrum, India and Department of Chemistry, University of Kerala, Trivandrum, India.
Sivakumar KC; Distributed Information Sub-Centre, Rajiv Gandhi Centre for Biotechnology, Trivandrum, India and.
Komalam RJ; Department of Chemistry, University of Kerala, Trivandrum, India.
Sreerekha KV; Department of Chemistry, University of Kerala, Trivandrum, India.
Rajasekharan KN; Department of Chemistry, University of Kerala, Trivandrum, India.
Sengupta S; Division of Cancer Research and Distributed Information Sub-Centre, Rajiv Gandhi Centre for Biotechnology, Trivandrum, India and Department of Chemistry, University of Kerala, Trivandrum, India ssengupta@rgcb.res.in.

Carcinogenesis ; 36(8): 883-93, 2015 Aug.

Article en En | MEDLINE | ID: mdl-26014355

Asunto(s)

Antineoplásicos/farmacología; Resistencia a Antineoplásicos/efectos de los fármacos; Tiazoles/farmacología; Subfamilia B de Transportador de Casetes de Unión a ATP/metabolismo; Miembro 1 de la Subfamilia B de Casetes de Unión a ATP/química; Miembro 1 de la Subfamilia B de Casetes de Unión a ATP/metabolismo; Animales; Antineoplásicos/química; Línea Celular Tumoral/efectos de los fármacos; Resistencia a Múltiples Medicamentos/efectos de los fármacos; Femenino; Humanos; Masculino; Ratones SCID; Simulación del Acoplamiento Molecular; Paclitaxel/farmacología; Tiazoles/química; Tubulina (Proteína)/química; Tubulina (Proteína)/metabolismo; Ensayos Antitumor por Modelo de Xenoinjerto

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiazoles / Resistencia a Antineoplásicos / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Carcinogenesis Año: 2015 Tipo del documento: Article País de afiliación: India

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