Atrazine Causes Autophagy- and Apoptosis-Related Neurodegenerative Effects in Dopaminergic Neurons in the Rat Nigrostriatal Dopaminergic System.

Song, Xiao-Yao; Li, Jia-Nan; Wu, Yan-Ping; Zhang, Bo; Li, Bai-Xiang

Song, Xiao-Yao; Li, Jia-Nan; Wu, Yan-Ping; Zhang, Bo; Li, Bai-Xiang.

Afiliación

Song XY; Department of Hygienic Toxicology, School of Public Health, Harbin Medical University, 157 Baojian Road, Nan Gang District, Harbin 150081, China. hedgehogviv@outlook.com.
Li JN; Department of Hygienic Toxicology, School of Public Health, Harbin Medical University, 157 Baojian Road, Nan Gang District, Harbin 150081, China. love512133nan@163.com.
Wu YP; Department of Hygienic Toxicology, School of Public Health, Harbin Medical University, 157 Baojian Road, Nan Gang District, Harbin 150081, China. Wuyanping_1964@aliyun.com.
Zhang B; Department of Hygienic Toxicology, School of Public Health, Harbin Medical University, 157 Baojian Road, Nan Gang District, Harbin 150081, China. sky_zhangbo_sea@163.com.
Li BX; Department of Hygienic Toxicology, School of Public Health, Harbin Medical University, 157 Baojian Road, Nan Gang District, Harbin 150081, China. libaix@ems.hrbmu.edu.cn.

Int J Mol Sci ; 16(6): 13490-506, 2015 Jun 12.

Article en En | MEDLINE | ID: mdl-26075868

Asunto(s)

Apoptosis; Atrazina/toxicidad; Autofagia; Neuronas Dopaminérgicas/efectos de los fármacos; Herbicidas/toxicidad; Animales; Proteínas Reguladoras de la Apoptosis/metabolismo; Atrazina/efectos adversos; Beclina-1; Caspasa 9/metabolismo; Neuronas Dopaminérgicas/metabolismo; Herbicidas/efectos adversos; Masculino; Mesencéfalo/citología; Mesencéfalo/efectos de los fármacos; Mesencéfalo/metabolismo; Mesencéfalo/ultraestructura; Proteínas Asociadas a Microtúbulos/metabolismo; Mitocondrias/efectos de los fármacos; Mitocondrias/metabolismo; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo; Ratas; Ratas Wistar; Proteína X Asociada a bcl-2/metabolismo

Palabras clave

apoptosis; atrazine; autophagy; dopaminergic neuron; neurotoxicity; wistar rats

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Atrazina / Autofagia / Apoptosis / Neuronas Dopaminérgicas / Herbicidas Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2015 Tipo del documento: Article País de afiliación: China

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