Influence of collagen addition on the thermal and morphological properties of chitosan/xanthan hydrogels.
Int J Biol Macromol
; 80: 225-30, 2015 Sep.
Article
en En
| MEDLINE
| ID: mdl-26123817
ABSTRACT
This study investigates the collagen influence on thermal and morphological characteristics of chitosan/xanthan hydrogels for potential tissue engineering applications. Anionic collagen was prepared by selective hydrolysis of type I collagen found in bovine tendons. Chitosan was obtained from the partial deacetylation of squid pen ß-chitin and xanthan was acquired from Fluka. The hydrogels were obtained in different ratios and were characterized by thermal and morphological analysis. FT-IR suggested only electrostatic interactions between NH3(+) groups of chitosan and COO(-) groups of xanthan and collagen. Thermogravimetric curves showed that hydrogels contain a great amount of water (above 98%) and the presence of collagen does not change this characteristic. Freezing-bound water transition in DSC curves was shifted to higher values due to the increase of water/polymer interaction, mainly when different ratios of chitosan and xanthan were used. SEM images showed sheet-form structures with the presence of collagen promoting an increase in pore size.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polisacáridos Bacterianos
/
Temperatura
/
Colágeno
/
Hidrogeles
/
Quitosano
Límite:
Animals
Idioma:
En
Revista:
Int J Biol Macromol
Año:
2015
Tipo del documento:
Article
País de afiliación:
Brasil