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Higher-Affinity Agonists of 5-HT1AR Discovered through Tuning the Binding-Site Flexibility.
Lian, Peng; Li, LinLang; Geng, Chuanrong; Zhen, Xuechu; Fu, Wei.
Afiliación
  • Lian P; Department of Medicinal Chemistry & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University , Shanghai 201203, China.
  • Li L; Jiangsu Key Laboratory for Translational Research for Neuropsychiatric-Diseases, Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
  • Geng C; Department of Medicinal Chemistry & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University , Shanghai 201203, China.
  • Zhen X; Jiangsu Key Laboratory for Translational Research for Neuropsychiatric-Diseases, Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
  • Fu W; Department of Medicinal Chemistry & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University , Shanghai 201203, China.
J Chem Inf Model ; 55(8): 1616-27, 2015 Aug 24.
Article en En | MEDLINE | ID: mdl-26131601
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Receptor de Serotonina 5-HT1A / Agonistas del Receptor de Serotonina 5-HT1 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Chem Inf Model Asunto de la revista: INFORMATICA MEDICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Receptor de Serotonina 5-HT1A / Agonistas del Receptor de Serotonina 5-HT1 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Chem Inf Model Asunto de la revista: INFORMATICA MEDICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: China