Estimation of divergence from Hardy-Weinberg form.
Twin Res Hum Genet
; 18(4): 399-405, 2015 Aug.
Article
en En
| MEDLINE
| ID: mdl-26138075
ABSTRACT
The HardyWeinberg (HW) principle explains how random mating (RM) can produce and maintain a population in equilibrium, that is, with constant genotypic proportions. When proportions diverge from HW form, it is of interest to estimate the fixation index F, which reflects the degree of divergence. Starting from a sample of genotypic counts, a mixed procedure gives first the orthodox estimate of gene frequency q and then a Bayesian estimate of F, based on a credible prior distribution of F, which is described here.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Teorema de Bayes
/
Genética de Población
/
Modelos Genéticos
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Twin Res Hum Genet
Asunto de la revista:
GENETICA MEDICA
Año:
2015
Tipo del documento:
Article