Genetically targeted fluorogenic macromolecules for subcellular imaging and cellular perturbation.

Magenau, Andrew J D; Saurabh, Saumya; Andreko, Susan K; Telmer, Cheryl A; Schmidt, Brigitte F; Waggoner, Alan S; Bruchez, Marcel P

Magenau, Andrew J D; Saurabh, Saumya; Andreko, Susan K; Telmer, Cheryl A; Schmidt, Brigitte F; Waggoner, Alan S; Bruchez, Marcel P.

Afiliación

Magenau AJ; Molecular Biosensors and Imaging Center, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA; Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA. Electronic address: amagenau@coe.drexel.edu.
Saurabh S; Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA.
Andreko SK; Molecular Biosensors and Imaging Center, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA.
Telmer CA; Molecular Biosensors and Imaging Center, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA; Department of Biological Sciences, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA.
Schmidt BF; Molecular Biosensors and Imaging Center, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA.
Waggoner AS; Molecular Biosensors and Imaging Center, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA; Department of Biological Sciences, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA.
Bruchez MP; Molecular Biosensors and Imaging Center, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA; Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA; Department of Biological Sciences, Carnegie Mellon University, 4400 Fifth Avenue, Pitt

Biomaterials ; 66: 1-8, 2015 Oct.

Article en En | MEDLINE | ID: mdl-26183934

Asunto(s)

Colorantes Fluorescentes/farmacocinética; Microscopía Fluorescente/métodos; Imagen Molecular/métodos; Proteínas/genética; Fracciones Subcelulares/metabolismo; Fracciones Subcelulares/ultraestructura; Colorantes Fluorescentes/química; Marcación de Gen/métodos; Células HeLa; Humanos; Proteínas/química; Proteínas/farmacocinética

Palabras clave

Atom transfer radical polymerization (ATRP); Biomaterial structure-property relationships; Fluorogen-activating proteins (FAPs); Genetically targetable macromolecules; Polymer modified cells; Protein polymer hybrids; Subcellular imaging; Targeting polymers to subcellular organelles

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fracciones Subcelulares / Proteínas / Imagen Molecular / Colorantes Fluorescentes / Microscopía Fluorescente Límite: Humans Idioma: En Revista: Biomaterials Año: 2015 Tipo del documento: Article

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