Mechanical phenotype of cancer cells: cell softening and loss of stiffness sensing.

Lin, Hsi-Hui; Lin, Hsiu-Kuan; Lin, I-Hsuan; Chiou, Yu-Wei; Chen, Horn-Wei; Liu, Ching-Yi; Harn, Hans I-Chen; Chiu, Wen-Tai; Wang, Yang-Kao; Shen, Meng-Ru; Tang, Ming-Jer

Lin, Hsi-Hui; Lin, Hsiu-Kuan; Lin, I-Hsuan; Chiou, Yu-Wei; Chen, Horn-Wei; Liu, Ching-Yi; Harn, Hans I-Chen; Chiu, Wen-Tai; Wang, Yang-Kao; Shen, Meng-Ru; Tang, Ming-Jer.

Afiliación

Lin HH; Department of Physiology, National Cheng Kung University, Tainan, Taiwan.
Lin HK; Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan.
Lin IH; Department of Physiology, National Cheng Kung University, Tainan, Taiwan.
Chiou YW; Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.
Chen HW; Department of Physiology, National Cheng Kung University, Tainan, Taiwan.
Liu CY; Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan.
Harn HI; Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan.
Chiu WT; Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.
Wang YK; Department of Cell Biology and Anatomy, National Cheng Kung University, Tainan, Taiwan.
Shen MR; Department of Pharmacology, National Cheng Kung University, Tainan, Taiwan.
Tang MJ; Department of Physiology, National Cheng Kung University, Tainan, Taiwan.

Oncotarget ; 6(25): 20946-58, 2015 Aug 28.

Article en En | MEDLINE | ID: mdl-26189182

Asunto(s)

Caveolina 1/metabolismo; Neoplasias/patología; Proteínas ras/metabolismo; Actinas/química; Animales; Fenómenos Biomecánicos; Proliferación Celular; Transformación Celular Neoplásica; Colágeno/química; Perros; Elasticidad; Inhibidores Enzimáticos/química; Femenino; Fibroblastos/metabolismo; Genes ras; Humanos; Células de Riñón Canino Madin Darby; Ratones; Microscopía de Fuerza Atómica; Microscopía Confocal; Microscopía Fluorescente; Células 3T3 NIH; Neoplasias/metabolismo; Fenotipo; Fosforilación; Neoplasias del Cuello Uterino/metabolismo; Neoplasias del Cuello Uterino/patología; Proteína de Unión al GTP rhoA/metabolismo

Palabras clave

caveolin-1; cell stiffness; matrix stiffness; mechanical phenotype; stiffness sensing

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas ras / Caveolina 1 / Neoplasias Límite: Animals / Female / Humans Idioma: En Revista: Oncotarget Año: 2015 Tipo del documento: Article País de afiliación: Taiwán

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