PSYCHOMETRIC HEPATIC ENCEPHALOPATHY SCORE FOR THE DIAGNOSIS OF MINIMAL HEPATIC ENCEPHALOPATHY IN ROMANIAN CIRRHOTIC PATIENTS--PARTIAL RESULTS.
Rev Med Chir Soc Med Nat Iasi
; 119(2): 368-73, 2015.
Article
en En
| MEDLINE
| ID: mdl-26204638
ABSTRACT
UNLABELLED In Romania, minimal hepatic encephalopathy (MHE) is underdiagnosed and undertreated in patients with liver cirrhosis. The psychometric hepatic encephalopathy score (PHES) is recommended as the first-line tool for the diagnosis of MHE. AIM:
To use PHES in a group of Romanian cirrhotic patients and highlight the relationships between demographic and biological factors and tests results. MATERIALS ANDMETHODS:
Of the 148 patients with liver cirrhosis admitted to the Iasi Institute of Gastroenterology and Hepatology between August 2014 and February 2015 only 80 who met the eligibility criteria were enrolled and completed the study. Blood samples for routine tests and serum ammonia were collected from all patients on the day of PHES evaluation.RESULTS:
In the study group (n = 80) mean age was 57.7 ± 8.5 years, and the average number of years of education was 11.2 ± 2.7. The main causes of cirrhosis were alcohol consumption (31 patients--38.8%), hepatitis C virus infection (29 patients--36.3%) and hepatitis B virus infection (17 patients--21.3%). Age, number of years of education, severity of liver disease (measured by using Child-Pugh and MELD scores) and some biological constants (albumin, bilirubin, International Normalized Ratio-INR) were significantly correlated (p < 0.05) with most psychometric tests.CONCLUSIONS:
PHES is a practical, objective and useful method for the diagnosis of MHE. Demographic and biological factors correlated with the results of the psychometric test. The PHES requires standardization before applying it in Romanian cirrhotic patients.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encefalopatía Hepática
/
Cirrosis Hepática
/
Pruebas Neuropsicológicas
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Aged
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Aged80
/
Female
/
Humans
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Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Rev Med Chir Soc Med Nat Iasi
Año:
2015
Tipo del documento:
Article