Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice.

Jang, Jae-Hwi; Baerts, Lesley; Waumans, Yannick; De Meester, Ingrid; Yamada, Yoshito; Limani, Perparim; Gil-Bazo, Ignacio; Weder, Walter; Jungraithmayr, Wolfgang

Jang, Jae-Hwi; Baerts, Lesley; Waumans, Yannick; De Meester, Ingrid; Yamada, Yoshito; Limani, Perparim; Gil-Bazo, Ignacio; Weder, Walter; Jungraithmayr, Wolfgang.

Afiliación

Jang JH; Division of Thoracic Surgery, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Baerts L; Department of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, Antwerp, Belgium.
Waumans Y; Department of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, Antwerp, Belgium.
De Meester I; Department of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, Antwerp, Belgium.
Yamada Y; Division of Thoracic Surgery, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Limani P; Department of Visceral and Transplantation Surgery, University Hospital Zurich, Raemistrasse 100, Zurich, Switzerland.
Gil-Bazo I; Division of Oncology, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Weder W; Division of Thoracic Surgery, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Jungraithmayr W; Division of Thoracic Surgery, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland. wolfgang.jungraithmayr@usz.ch.

Clin Exp Metastasis ; 32(7): 677-87, 2015 Oct.

Article en En | MEDLINE | ID: mdl-26233333

Asunto(s)

Adamantano/análogos & derivados; Antineoplásicos/farmacología; Neoplasias Colorrectales/patología; Neoplasias Pulmonares/secundario; Neoplasias Experimentales/tratamiento farmacológico; Nitrilos/farmacología; Pirrolidinas/farmacología; Adamantano/farmacología; Animales; Apoptosis/efectos de los fármacos; Línea Celular Tumoral; Dipeptidil Peptidasa 4/metabolismo; Humanos; Etiquetado Corte-Fin in Situ; Masculino; Ratones; Ratones Endogámicos C57BL; Vildagliptina; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

Apoptosis; Autophagy; CD26/DPP4; Lung metastases

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_colon_rectum_cancers / 6_other_respiratory_diseases / 6_trachea_bronchus_lung_cancer Asunto principal: Pirrolidinas / Adamantano / Neoplasias Colorrectales / Neoplasias Pulmonares / Neoplasias Experimentales / Antineoplásicos / Nitrilos Límite: Animals / Humans / Male Idioma: En Revista: Clin Exp Metastasis Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Suiza

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